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–The sample and liquids used in HPLC and LC/MS are chemicals which the detectors may detect. RobBurgess.
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  • Never use Argon or Nitrogen to.
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    For example, if you use a reversed phase method with UV-detection, you can add 0.

  • Baseline Problems A16089 This document is concerned with diagnosis: the process of going from unexpected behavior of the GC to the probable location of the difficulty (causes).
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    This.

  • This video shows how to use the interactive HPLC Troubleshooter to identify potential causes for the problem.
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    Offset can be described as a series of steps.

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  • The effect is more pronounced with small-volume LC columns.
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    To check the flow cell, remove it from the instrument and examine.

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    UV detector – flow cell and lamp A mechanical problem with the flow cell is a common cause of baseline anomalies.