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Where did the BLOSUM62 alignment score matrix come from? Nat Biotechnol. For details about each model, see the list of built-in score matrices.
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  • To quantify the degree of impact of a variation on protein function, we define a delta alignment score.

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    Feb 4, 2021 · In the homologous alignment data that BLOSUM62 was trained on, leucine/leucine (L/L) pairs were in fact more common than tryptophan/tryptophan (W/W) pairs (p.

  • Where did BLOSUM62 come from? You have full access to this article via your institution.

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    For example, the definition of the widely used BLOSUM62 matrix varies depending on the source, and even a given source can provide different versions of "BLOSUM62" without keeping track of the changes over time.

  • 1038/nbt0804-1035.

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    The wikipedia article on BLOSUM has a good explanation, check the section on scoring.

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